TransMed7’s Platform Technologies

TransMed7 develops medical technologies as various device platforms.  Within each single platform of technologies developed for use in a specific medical field, we further generate individual device models that, while designed from one basic concept, are able to address different needs of physicians and their patients.

In addition, several of TransMed7’s new platform technologies intended for use in separate medical fields utilize a “working element” based on TransMed7’s unique, patented Zero5 technology.  This working element is forward-cutting and forward-coring as it moves through, then parts off (severs) tissue samples of different densities ranging from fatty tissues to cartilage and bone.  TransMed7’s Zero5 technology is designed to enable our devices to reliably and consistently obtain full-core, uniform-diameter samples with intact architecture from all of these tissue types.

TransMed7’s Patented Zero5 Technology:

TransMed7’s Zero5 technology consists of a patented, simple element made by fusing three coaxial hypotube segments, laser cut and laser welded together, forming a single, wide open structure from front to back.  The front end of the working element may be formed into twin cutter blades that can cycle from closed to wide open and back again while being rotated to safely approach, core, and sever target tissue.  The main tubular section continues back from the working end, providing a wide-open pathway to serially transport multiple tissue samples via a flush and vacuum circuit into a preservative-fillable, image-ready, detachable, labeled, and sealed chamber for safe transfer to a histopathology lab for complete analysis.

Zero5 technology is designed to enable the following health care technology advancements during a biopsy procedure:

  • Zero-1:  Zero dead space beyond what the tip touches and cores
  • Zero-2:  Zero host tissue nor lesion tissue displacement
  • Zero-3:  Zero lesion length restriction
  • Zero-4:  Zero tissue bias*
  • Zero-5:  Zero cored specimen distortion

* All caliber devices from 21 gauge to 8 gauge core all tissues the same, from lung to bone, without bias.


TransMed7’s Zero5 technology is further illustrated in the CAD (computer aided design) drawings below:

Zero5 CAD head on view

Head-on view:  No mechanisms project inside or outside of the walls of the tubular element, providing wide open space for tissue acquisition and minimal resistance to passage through tissue.

Zero5 CAD side view 1Zero5 CAD side view 2

Side views, open configuration:  TransMed7’s patented tissue penetration, coring, part-off, and transport mechanism consists of three thinwall hypotubes laser cut and laser welded into a robust single-piece working element.

Zero5 CAD view oblique

Profile view:  Patented opening-closing mechanism is completely contained in the wall of the monolithic structure, providing the simplest, lowest profile, and most robust working element.  The need for any firing mechanism is eliminated.  Lowest cost, highest yield, simple manufacturing process is provided inherently.  High-volume optimized, laser cutting, welding, and polishing – utilizing built-in reference points – are followed by fixture-based precise sharpening.

Zero5 CAD view side 3

Side view, closed (tissue penetration and part-off) configuration:  Simple, robust monolithic structure incorporates a built-in closing mechanism, providing positive, rotating tissue part-off and capture.  The asymmetric tip creates a flashing reflection during rotation that is easy to home-to and track under ultrasound imaging.  Closed beak, gently rotating, non-sharp dissection minimizes tissue disruption during the image-guided, gently controllable approach to the target, and is selectable to sharp dissection (open beaks) when encountering tough tissue to minimize the approach effort further (as desired by the operator), completely eliminating the need to “fire” (spring-loaded forward snap) the needle into tissues.

The video below shows five different TransMed7 device platforms that have been generated utilizing TransMed7’s Zero5 technology.


TransMed7’s devices are designed for “minimally disruptive access”, meaning that our devices are introduced to the treatment or surgery site via a natural body orifice or via a small incision made in the skin.  One or even multiple procedures can be accomplished in this manner as is necessary.

Further information for many of TransMed7’s new platform technologies that are currently under development can be found using the links below.

SpeedBird 38 & SpeedBird Universal






Osprey & Thunderbird

Mustang, Hurricane, Zeppelin, & Warhawk